DPCstruct | MC59896

Metacluster Properties and Pfam Annotations

Number of structural domains4986
Mean domain length (aa)194 ± 33 aa
Standard deviation of domain lengths33.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.33
Pfam Score88.23
Assigned Pfam label(s) PF05731- CL0692- PF11957- CL0616- PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4KCY6 65-258 None
S3DV85 581-785 None
A0A497N3M1 654-823 None
A0A497N0H5 124-316 None
A0A7Y3G2B9 26-222 None
A0A2D6R808 372-567 None
A0A7R9JHW9 425-554 None
A0A7R9JCV4 543-773 None
A0A6L9ZUR4 992-1201 None
H6Q622 229-397 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.