DPCstruct | MC59896

Metacluster Properties and Pfam Annotations

Number of structural domains4986
Mean domain length (aa)194 ± 33 aa
Standard deviation of domain lengths33.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.33
Pfam Score88.23
Assigned Pfam label(s) PF05731- CL0692- PF11957- CL0616- PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I3DTY7 9-203 VSGTANIAILLDASGSMAQKIGGKTKMDLAKEAVNQFVSSMPEGSNVSLRVYGHKGSNSDNDKKLSCGSTEMVYDLKPYNAADFKAS…
U9UKY4 2-118 EVDLCFVMDCTSSMGSHIEGAKSSIKKIVDYMANMKPAIVVRVGFCGYRDHCDGSNRLQIIEFTTSCNEFKNNVSNVSALGGGDAPE…
A0A806K218 28-185 None
A0A1Y1NBH0 75-278 None
A0A7R9L5J6 7-227 None
A0A7R9KV68 14-228 None
A0A7R9KDJ1 1023-1213 None
A0A5S6QQJ4 327-516 None
R6Z992 793-987 None
A0A3C0GD64 166-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.