DPCstruct | MC5989

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)121 ± 11 aa
Standard deviation of domain lengths10.53
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score87.52
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J0AYY8 24-152 EHHLNQEDVDMANGLVAHIERTRCSRQPKIGDRVVYTSIYGDWYGNAVIEKFEDGECSLCLSPYVPFIWKSPLGIGCSVSGGPFTSV…
A0A6M3M2G8 19-146 PESTGRHILDTIAVVEEHLNGGIELTKPMPGDLVMILNSGDCLVKNRSLGIIEGIVGEYRNHYLVCFNDSTFNDGKIVNASGGPAYC…
A0A7W3VUP2 60-191 None
A0A523D6P5 15-151 None
A0A2S0N6A5 9-120 None
A0A523TC42 2-107 None
A0A218PUL2 15-139 None
A0A5N7MPM5 81-195 None
A0A543K3Z6 4-124 None
A0A2A7EIL5 17-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.