DPCstruct | MC59807

Metacluster Properties and Pfam Annotations

Number of structural domains182
Mean domain length (aa)162 ± 35 aa
Standard deviation of domain lengths35.21
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.94
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.57
Pfam Score94.24
Assigned Pfam label(s) CL0025- CL0413- PF15091- CL0329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453EQ19 6-164 PIAFRKELDGIIVDVSLQWCSDSYSDTVLGYANSIRTVDGGTHIEGLKTSLTRTINSFAKKSKIMKDKDISLSGEHVREGMTCIISV…
A0A3S5DJW0 2-113 TAEKENIVVELSMQWNDSYQETLYCFTNNIPQRDGGTHMAGFRAALTRTLNNYIESEGYAKKAKVSPTGDDAREGLTAILSVKVPDP…
A0A7J4EYW2 304-475 None
A0A1I8FTX2 542-682 None
A0A7I4E7S0 3-247 None
A0A855HXD0 6-161 None
C0AG68 4-162 None
R1BRX6 314-488 None
A0A1P8BB88 54-237 None
A0A2A2KQS6 525-669 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.