DPCstruct | MC59792

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)244 ± 28 aa
Standard deviation of domain lengths27.89
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score78.91
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)35.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A392M1N1 1-222 MEKPFPLPRCFGSRDFLEKNPPMVAAVEKSLILDMGPAARQEELTQDLTAMMRVMETVMVLNDEQGSSNREMAKLRTRNEKLEARAL…
A0A2Z6PKP1 3-180 DMGPEALKNELADAMVAAFKLMEISSFLNGRECKYLEERDAAREEVVLVNQRLEQTKVNHAAYKEKFKLQVGLVTKLDEKETEAARL…
A0A392NFQ0 20-263 None
A0A2K3JL32 10-229 None
A0A2Z6NXH5 143-394 None
A0A2Z6MQF8 576-836 None
A0A2Z6MUU5 422-688 None
A0A392LXQ3 1-249 None
A0A2Z6PS72 1-271 None
A0A2Z6PUM6 239-509 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.