DPCstruct | MC59589

Metacluster Properties and Pfam Annotations

Number of structural domains562
Mean domain length (aa)185 ± 32 aa
Standard deviation of domain lengths31.89
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.18
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.76
Pfam Score75.39
Assigned Pfam label(s) CL0023- CL0418- PF04860- PF10123- CL0201

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M5YUP6 22-151 None
A0A2D6NGJ8 448-614 None
A0A7L5Z251 12-181 None
A0A662VGZ3 59-244 None
Q1QI78 552-727 None
A0A176UIE7 38-232 None
A0A6B2XF68 36-229 None
A0A812NR94 683-881 None
A0A2E4JJB2 2-196 None
A0A2E4W3R1 54-245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.