DPCstruct | MC59564

Metacluster Properties and Pfam Annotations

Number of structural domains298
Mean domain length (aa)173 ± 32 aa
Standard deviation of domain lengths31.84
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.20
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.94
Pfam Score32.05
Assigned Pfam label(s) PF20129- PF05936- PF20747- PF16075

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6M0A316 3-179 EIKRLNYFTSQFLVEKDFSDEQDYHRRMRHLHNRSLHTWGVVEGLEINKSGDKQVSVNNGMAIDSEGKEIVVLDEQPADIKTISLSE…
A0A166TZH6 7-145 TFFSPSGSEYPITSDADAKLYMMLSGVDYTTFKRKNWTPMTSVGLTRTYTNTSFVVAGRYFELKNHMITLTPSTKSFVHVNIDLSTP…
A0A810LFT8 16-231 None
A0A2W1V9Y8 4-147 None
A0A4R1R5L2 5-153 None
A0A2S1LTV3 8-152 None
A0A538QBP2 2-172 None
E9KSL3 144-333 None
A0A396QEW2 1-124 None
A0A7W5IHK9 3-247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.