DPCstruct | MC59452

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)293 ± 30 aa
Standard deviation of domain lengths30.49
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score79.53
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.58
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D2TB56 42-347 FSPDIPEPTVTSLIRKILYPERVCNNDKNVVGIYRAKDITSSHPFYLRAVALKITHHISHIREVLIPAVSRALNELPWNYESYLGNV…
A0A7Y8BRI5 22-262 AVRVSRGKVMARGVTELRKSYPEQASNFDLGHEFLRVALDEAVNKVSSDNLSHEYTALPRRILGSTESWQELKPVLLERFEGLRVAA…
A0A4R1NFX0 177-506 None
A0A839VP04 229-473 None
A0A2K4IIT5 82-377 None
A0A7X1YA62 55-357 None
A0A7X2BVT0 424-732 None
A0A844C6N5 327-654 None
A0A2T5DD26 138-423 None
A0A848MUN3 71-389 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.