DPCstruct | MC59405

Metacluster Properties and Pfam Annotations

Number of structural domains258
Mean domain length (aa)111 ± 19 aa
Standard deviation of domain lengths19.13
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.70
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)20.49
Pfam Score98.65
Assigned Pfam label(s) CL0041- CL0431- CL0093- CL0661- PF00643

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J8EBN6 36-150 MDKKDKRTLLQCRTKLVEDLDVQPVLDHLFEAGILTADQVERISGNDTSARKNRALIDILPRRGPTAFKCFLESLINSDQSHLNAYL…
A0A7R9FT54 206-290 PHQNAITSNWKDLIADMDVESVENYMIIKNKLPLDKREELKMEKVARRRRSLLLHYVHDRDEDVFLAFRDGLVDADQTHLAEKLK
C3ZGJ7 1-95 None
A0A2B4S546 57-186 None
A0A2B4S753 1-97 None
A0A2B4S6M9 284-383 None
A0A2C9KEH7 1-119 None
R7UHF9 1-117 None
A0A2R2MQ83 402-500 None
R7UQK2 1-96 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.