DPCstruct | MC594

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)635 ± 74 aa
Standard deviation of domain lengths74.44
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score75.34
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.24
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)15.69
Pfam Score100.00
Assigned Pfam label(s) CL0389

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q8WTL4 5-529 KKFVLTETFEKLSTIKEDELITCLPREHFDIPWAISIKKLDGNFYVYLCCEKELGYPSNWSIEYKSTIQIMKPGGMGVSRNCKGIFD…
A0A1Y2FE92 139-812 ESQEKLQHEPVPPHLEQSPVQSPVQIPVSTTERDKFINKLKGLLKNVTKKEYPTLEEKFIELEIENWDQLKDLKYSPEYVIGDNKWR…
A0A1E5VPH5 12-685 None
A0A0E0R0E9 95-726 None
A0A0D9XKN3 8-610 None
A0A6A5DS03 1-631 None
A0A7J8Q788 14-653 None
A0A1Y1WY84 8-830 None
A0A6P7VGV5 413-1083 None
A0A438CWF4 2-707 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.