DPCstruct | MC59399

Metacluster Properties and Pfam Annotations

Number of structural domains844
Mean domain length (aa)124 ± 24 aa
Standard deviation of domain lengths24.40
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.26
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.09
Pfam Score84.90
Assigned Pfam label(s) PF09388- PF13788- CL0237- PF02875- CL0062

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V2BYV9 25-134 YKPRQPNMEITEEKSNDVSIIALNGRLNVTTTADLEKAFNKLFDENCTKILVDCRDLEYISSAGLRVLLAAAKQFKKISGEIALSGL…
A0A3B8V839 344-465 TPPLPDHHATSLVEITRQGGILLVKPAGPSIGQREAPIIQEAVTPYIEEMGKSLDHLVMDLSGVTFMSSMGLGMCISLRNGAVAVKS…
A0A7S4R6L0 119-240 None
A0A4Q4KF71 6-125 None
A0A0S8BHB0 95-249 None
A0A220UMF1 2-95 None
A0A426TR84 433-555 None
A0A4V5NI77 1016-1196 None
A0A7S4RA56 562-679 None
A0A7Z0GJD7 1-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.