DPCstruct | MC59318

Metacluster Properties and Pfam Annotations

Number of structural domains962
Mean domain length (aa)152 ± 25 aa
Standard deviation of domain lengths25.07
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.06
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)15.84
Pfam Score67.18
Assigned Pfam label(s) CL0126- PF17659- CL0255- PF18212- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S4DYU4 12-151 QALFISPRKGESVKLGHETASFGKQQPYDVRGLIVRPFDEFLCSETGNYSHFKDNIALATRGNCSFFQKAWLAAEAGAKALIIGNNA…
S4RY53 28-199 DDGLENVHPEAAKVPHWVRGRESATMIEPRNHSLAILGLGGSVGTPPEGTTADVLVVSSFDELRKLGTAAKGKIVVYNEPYVSYGET…
A0A068UUI8 1-131 None
A0A7N2KM15 880-1005 None
A0A2G8L5H6 89-231 None
A0A453DN76 257-411 None
A0A7S1ULS2 559-746 None
A0A1B0BXD4 140-292 None
A0A1R3KKZ4 2-120 None
A0A803JSA5 21-170 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.