DPCstruct | MC5929

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)128 ± 23 aa
Standard deviation of domain lengths22.50
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)45.79
Pfam Score93.55
Assigned Pfam label(s) PF00206- PF10415

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A251UI07 9-127 NRLWGAQTQRSLQNSEIGGERERMHEPIIRSFGILKKCAAKVNMEYGLDPSIGKVLMEAAQEVAEGKLNDHFPLVVWQTGRGTQSNM…
A0A5P1EC12 3-116 EPIIRAFGVLKKCAAKVNMEYGLDPAIGKAIIQAAEEVAEGKLNDHFPLVIWQTGSGTQSNMNANEVIANRAAEILGHKRGEKFVHP…
A0A482X0U8 61-195 None
A0A378VZ17 2-118 None
A0A835TJT0 2-117 None
A0A4R7AJ33 7-124 None
B6A0Z2 19-154 None
A0A844VWK8 2-115 None
A0A2P5BJE1 469-601 None
R9AA50 529-660 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.