DPCstruct | MC59275

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)172 ± 33 aa
Standard deviation of domain lengths33.23
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.92
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)18.43
Pfam Score59.13
Assigned Pfam label(s) PF08223- CL0728- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A522SKY8 1-135 MLPQAEDHAEFFAQLADAVRKQNGSATVFLVQAMSPTEQETLISRFQADRAREYDEFAERSRGFLDEIAKETGLQKFTFAELEEIED…
A0A1S2GNX5 14-199 ARASDPWLLVSFSVPEAQRGQRHKIRSGLSRMGFGVVSAGLCVAPGHVYNEALEYLQDNDLLQFVDFFHANHGGPEELRTKVAQWWD…
A0A7X1U0U1 3-149 None
E4THB5 3-131 None
A0A7C6EIM1 14-173 None
A0A2N6RHE7 7-146 None
A0A1G3MZU8 25-264 None
A0A853DST4 48-257 None
A0A843T585 2-159 None
A0A840WWW0 26-241 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.