DPCstruct | MC59243

Metacluster Properties and Pfam Annotations

Number of structural domains363
Mean domain length (aa)161 ± 30 aa
Standard deviation of domain lengths29.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score82.38
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.94
Pfam Score57.98
Assigned Pfam label(s) PF14736- CL0663

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0U5CGP0 11-171 KELHEDGERVLIVPMGGVEFVAFNTKPAIGTIGLNSCSVVIIASQHGAILAHIPPRLHLTSDDLHEGDRNVRRMMALVKAEHDRYKP…
A0A1H2IA19 50-216 TVVDGPVTEPVPATDALVTTTPGLALAVLSADCVPVLLSDDEAGVIAGVHAGRVGARIGIVRETLKVMVELGARISSIGAFLGPAAS…
A0A318YFI2 467-675 None
A0A0W0Z9C3 81-244 None
H9G882 108-261 None
A0A517T2T4 26-157 None
A0A2V1DGM9 277-475 None
A0A7C2CNM4 41-199 None
A0A178EGC6 345-545 None
A0A518HVF6 10-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.