DPCstruct | MC5921

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)280 ± 56 aa
Standard deviation of domain lengths55.57
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score75.39
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)17.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2WER8 20-323 GLPLPLPSPPAMNHLNAPYQGQGAGAHAMVPMLHQAPGARDTEANRKESLYLSHLEVRARMPLMMNSITGQYQGFVRSYRDYDVVNC…
A0A6A6WYW1 11-210 AQPYQFDDSGVPKLAFSNDQAAAHAYRRRSTMPPQLDPESDPTIVEVREAQERWISDMVQAVFNHDGVPEAVNLPAYTMFMHGSRTV…
R1EFC7 348-629 None
A0A3M7M1X7 112-497 None
A0A6A5ZMD9 37-272 None
A0A6A6Z8U0 188-467 None
A0A6A5ZJ90 7-202 None
A0A6G1IGS6 1-196 None
A0A2A9PMA9 68-421 None
A0A6A5QRI1 1-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.