DPCstruct | MC592

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)105 ± 10 aa
Standard deviation of domain lengths10.33
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)35.30
Pfam Score100.00
Assigned Pfam label(s) PF10270

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A665WS90 2-107 ASSFWKGVVGVGLFALAHAAFSAAQHRSYLRLTEKENETLPIDIVLQTLLSFVMTCYGIVHIAGEFKDMDASSELKNKTFDTLRNHP…
A0A1Y2F0Z2 1-97 MLKYAICCFGILLLSHASYSALQQIRIQRNQENGNQSLPYDIIAECMASIVVMLIGLTISTKNFENISIEETNKQNKMDSINTHSDF…
A0A183E7H4 1-102 None
G0MV74 2-104 None
A0A7J6Z5T3 101-224 None
A0A7S2SS50 8-121 None
A0A445CR86 41-152 None
M7Z2U1 1-79 None
A0A078I5C2 50-163 None
A0A834JRI4 43-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.