DPCstruct | MC59187

Metacluster Properties and Pfam Annotations

Number of structural domains280
Mean domain length (aa)78 ± 15 aa
Standard deviation of domain lengths14.63
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.62
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)28.68
Pfam Score99.68
Assigned Pfam label(s) CL0451- PF19548

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5MQJ0 89-179 None
A0A6P6CVE2 251-316 None
A0A482WKG6 27-113 None
A0A162R2E4 25-135 None
A0A835NDC7 91-181 None
A0A3L8DYI5 285-353 None
A0A0M4EJX2 252-314 None
A0A6V7U7P4 452-526 None
A0A6P6C4X0 35-120 None
A0A4Z2E461 66-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.