DPCstruct | MC59165

Metacluster Properties and Pfam Annotations

Number of structural domains246
Mean domain length (aa)146 ± 26 aa
Standard deviation of domain lengths26.40
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.96
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)10.95
Pfam Score60.78
Assigned Pfam label(s) CL0691- PF14065- PF11863

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E3C317 4-104 QNLKNLLLTIGPPVFHYFASGQTRNYIVWAEDGEGASGHADNKKTTQVISGTIDYFTKDEFDPVTEQIQGKLNDSRISWRLNSVRHE…
A0A0X3TDT3 4-138 VVIEMQQRLDATGAFAKVADSVALTELSAKLIHGQASAWVGELSSLPGQNTRDIGDPVQFEQQVFGVVIGVRSINDPHGSAAKQTLQ…
A0A0G0M6Z1 859-991 None
A0A1Q6KJJ7 7-110 None
A0A0M4CVP9 1-146 None
A0A1H2TS52 9-189 None
Q7VPF0 6-184 None
A0A3S4D127 4-133 None
A0A350PH60 47-231 None
A0A1V5V515 4-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.