DPCstruct | MC59141

Metacluster Properties and Pfam Annotations

Number of structural domains802
Mean domain length (aa)142 ± 34 aa
Standard deviation of domain lengths34.15
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score84.15
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.73
Pfam Score96.37
Assigned Pfam label(s) PF06421- CL0029- PF11961- CL0395- PF06844

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q54RP1 135-292 NNSYYNKRLKFDKDFRILLLKSLGIMFLVRTYVVELTYCQGTSMEPTINTGDFIFINKLSKDYKVGDLITAACPTNQFSICKRIRFV…
A0A285QVE8 2-95 LRAVLAAAGRARLRTRGESMLPAIVPGTVVTVEALPLPRVVPGDVVAAAVGARIIVHRVVATAPDVLLTAGDNLPLLDPVVGPDGYL…
A0A7C5YZT4 7-125 None
A0A6T7HGH5 270-413 None
A0A523QD72 254-402 None
A0A811MPL1 82-227 None
A0A3D5DU55 2-107 None
R5M1Y7 196-315 None
A0A523QEB7 33-159 None
A0A0E0GU76 289-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.