DPCstruct | MC59140

Metacluster Properties and Pfam Annotations

Number of structural domains5993
Mean domain length (aa)109 ± 21 aa
Standard deviation of domain lengths21.49
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.64
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)16.10
Pfam Score85.79
Assigned Pfam label(s) CL0221- CL0020- CL0015- PF16366- PF09004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A195DME6 530-645 None
A0A0E0LNM4 34-106 None
A0A0E0LJ25 573-681 None
A0A7J7B491 424-541 None
A0A1Y2FP27 682-777 None
A0A1Y2FAQ4 257-345 None
A0A445L4G6 294-397 None
W3VR45 46-166 None
A0A5B6WV76 33-151 None
A0A2P5YGA4 1-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.