DPCstruct | MC59140

Metacluster Properties and Pfam Annotations

Number of structural domains5993
Mean domain length (aa)109 ± 21 aa
Standard deviation of domain lengths21.49
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.64
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)16.10
Pfam Score85.79
Assigned Pfam label(s) CL0221- CL0020- CL0015- PF16366- PF09004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2G1N4 216-337 None
A0A1Y2FZP4 203-329 None
A0A835KJS2 303-381 None
A0A699ITC2 18-125 None
A0A5A8DVV8 312-409 None
A0A5A8E014 105-196 None
M1HAJ5 6-121 None
U9SVQ1 7-89 None
A0A0B2VBL2 188-274 None
A0A0B2UVY6 164-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.