DPCstruct | MC58976

Metacluster Properties and Pfam Annotations

Number of structural domains206
Mean domain length (aa)116 ± 16 aa
Standard deviation of domain lengths16.36
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score90.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.72
Pfam Score98.84
Assigned Pfam label(s) CL0158- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C2RY81 78-193 QKVPVLMYHAIDDYHGQGIKDLFVSPANFEAQMKYLKDNGYTLLTFERWGDINKVNKPIFVTFDDGMKNNMNAFHVLQKLKDDTFKP…
A0A0L6JL79 36-142 LKKGLYIFFYHSFVDTEKCKKDGRLISLSSVDRKAFESQLKYFKTDYTVITLDEAYELMKSNKPLDRRYLVLTIDDGYKDNFIYGYE…
H1LI18 35-163 None
A0A8B5XFR5 112-290 None
A0A1E2UU27 74-172 None
A0A2X2RNR1 39-142 None
A0A7G8TAR4 2-109 None
Q1AUP9 6-122 None
A0A7W1BLH3 698-809 None
A0A0M2HXJ0 193-340 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.