DPCstruct | MC58949

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)178 ± 32 aa
Standard deviation of domain lengths31.95
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score73.93
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)28.67
Pfam Score97.22
Assigned Pfam label(s) CL0063- PF07923

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7IXQ1 8-156 IPKLREILRRQRGDSESSDAPDVEFVYDDADEHTVELAELYSYTEYPDFALNKQAFTEHFAQYGRHDGGWSTANDSLRSNYLLHLLN…
A0A822B9X8 4-162 ASVVRRVVNKPRDVIPRNPAINPDTLLDVPEFNFIYNDSDTIYAEIAELYTYSEEPEFVWNAEAFNILFQAKYGENKKWKDYSKDDK…
A0A1I8IRI2 8-224 None
A0A369S8T2 1-174 None
A0A1Y1VFE7 116-280 None
A0A3Q0IYP9 1-119 None
A0A3M0IPC7 19-207 None
A0A4P9XEJ0 100-278 None
A0A183UWB6 61-238 None
A0A5K3FGP0 1-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.