DPCstruct | MC58948

Metacluster Properties and Pfam Annotations

Number of structural domains554
Mean domain length (aa)71 ± 10 aa
Standard deviation of domain lengths9.85
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.65
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)24.42
Pfam Score98.30
Assigned Pfam label(s) CL0056- CL0159- CL0004- CL0005- CL0602

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E7FCC2 141-201 TLITCDNPTPPEHGNVMFRSPVLYNDVIKYSCQENYTLVGNRSLTCGDDWDYNFPPPKCEA
A0A7J7IVD2 32-107 PVSLMGTATSCGRPPYVEHGSFKVTSGYKFTDHVEYTCFSDFMLNGVNFAVCLSNGSWSKPPSCLPAARKCNRKSN
A0A2G8LAJ3 19-85 None
A0A2D0PM40 163-224 None
A0A2D0Q941 578-658 None
A0A2D0QGZ3 80-141 None
A0A2I4CW32 3-95 None
A0A3B5QT18 133-208 None
A0A7R8X6G6 136-202 None
A0A7R8X1H5 195-283 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.