DPCstruct | MC58844

Metacluster Properties and Pfam Annotations

Number of structural domains494
Mean domain length (aa)654 ± 151 aa
Standard deviation of domain lengths151.23
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score65.70
Mean fraction of residues predicted as intrinsically disordered0.69
Mean length-normalized TM-Score0.17
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)15.23
Pfam Score3.18
Assigned Pfam label(s) CL0679- PF09738- PF13868- PF04849- PF15743

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y3EUA0 46-682 KSVDDESSNWIASRMGIDAKSRTMAAWPVLSSSGSPPCSTDSGDEASAFAGVEYDVHSCVNFLISEVCSRVEPTTMTKEDDYCSDPL…
A0A7E6DGL4 1-572 MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTE…
A0A2H3C2H6 228-1005 None
A0A2G2XDU9 2-432 None
H9GL85 252-1139 None
A0A1V9Z2X2 83-701 None
A0A1V9YZ75 13-775 None
A0A0S7DYI3 1-724 None
A0A4W2G7E5 43-826 None
A0A3Q0F9G1 100-645 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.