DPCstruct | MC58837

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)155 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score86.62
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.72
Pfam Score91.30
Assigned Pfam label(s) PF12896- CL0063- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y3EJY6 14-161 LCKVKQNKQDRQFCFTCGHFVLPEERSEHVQHKLKFNITNRLLNRPCMWLTASKSEKKEAQYWFSDSCAKFLAKLPLELSFDHVLCI…
A0A6J0BRS6 94-240 LNEILAINPIRRIYCHDCGRLSFVSEKHKHRGHDIIENLTDHQLRHPTEFLRPLENPKKEAQYLFSDQSVSDIIFMLLNLGAKHILC…
A0A2H2IHS7 154-265 None
A0A183H7J4 116-231 None
A0A368FQA4 4-144 None
A0A7R9PPZ8 129-249 None
A0A0N4WKQ0 61-156 None
A0A834PBK7 79-273 None
A0A5A9PYS4 18-145 None
A0A4Z2BM65 7-197 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.