DPCstruct | MC58555

Metacluster Properties and Pfam Annotations

Number of structural domains120
Mean domain length (aa)96 ± 13 aa
Standard deviation of domain lengths12.93
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score87.78
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)24.32
Pfam Score77.94
Assigned Pfam label(s) PF16191- CL0105- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2M8EFG3 322-410 GLMCIALGKTITGATQANPVALTVAAHGYTTGNVVQIDSVEGMTQLNGKLYTITVTDANTITLNAVDGTAFTAYTSGGITTKGVFYA…
A0A661R439 395-479 GVTCIAADKTITAATNANPCQVTAVGHGRSTGDYAMVRSVGGMTEINDKIFTITVVDADNFTLDGVDSTAFAAYSSGGSITVGDF
A0A834T8L7 241-338 None
A0A1G0RDV6 3-93 None
A0A2V6GV06 251-357 None
A0A222EBL2 783-887 None
A0A317HPX7 71-161 None
A0A672GT43 166-260 None
D5SZF6 31-122 None
A0A3N5F2L2 148-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.