DPCstruct | MC58545

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)277 ± 59 aa
Standard deviation of domain lengths58.99
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score72.96
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)28.13
Pfam Score81.35
Assigned Pfam label(s) CL0644- CL0124- CL0602- CL0016- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2B4SFK2 180-394 SCIFYEYKGEFCKDIITSLYVYGNQSTLDYGEKETNTFGGYFNLFEISERCKPVIRDLYCRYHFPPCDETLGEPKDRGLCQRSCLYL…
A0A671L5Q7 7-284 EGFCQPYRGIACARFIGNRSIFVDSLQMQGEIETQITAAFTMIGTSNHLSDRCSQFAIPSLCHFAFPTCDRSSGMDKPRDLCKDECE…
A0A6P4Z756 526-780 None
A0A1X7U1V3 22-348 None
A0A2P8Z9A9 2-280 None
A0A553P113 1-261 None
A0A2B4S9F6 41-304 None
A0A7R9KMF6 4-332 None
A0A6A4V9L4 229-468 None
A0A6I9YP43 10-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.