DPCstruct | MC58462

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)109 ± 22 aa
Standard deviation of domain lengths21.66
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.24
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)46.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A224Z7K0 17-96 YCEEPASVFPFEWPDDITKWPVCRRSHASRKVPDAHMSCEVVGRPCCIGVYGECHITTRDYCDFVGGFFHEEAALCSQVS
A0A0S7G3R0 124-270 STLAEWVKWPNPTLNTPQLNGKDRQYGSVCHQDPSICVEPASMYPHEWPDDITKWPICTRYNTGNHTNLPHIDCTITGRPCCIGTKG…
A0A183B183 302-433 None
A7RJJ9 176-274 None
A0A183RBR3 119-201 None
A0A817J5E0 373-500 None
A0A183KSE1 259-352 None
A0A7R8WKD8 2-99 None
A0A1S8WNG5 93-188 None
A0A1S3JGA4 283-387 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.