DPCstruct | MC58138

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)371 ± 74 aa
Standard deviation of domain lengths73.74
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.29
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)39.94
Pfam Score73.20
Assigned Pfam label(s) PF04561- CL0410- PF04563- PF04567- PF10385

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7T0BRP2 117-504 ILHPNSEKFYINLYRILKSTEFSNTKNVKDYIKNLFQNSKNYDLSDTGRFRLNQKLNIYIPKQVRLVTIVDILLAVKLLIKLYSNKS…
A0A076VES1 1-284 IRPVVASIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLASYGRV…
A0A7C0X2F9 2-316 None
A0A6B9VA91 2-344 None
A0A4S8I2F4 86-456 None
Q8HTL6 412-818 None
A0A345HH11 219-590 None
A0A426H4V6 13-333 None
A0A244C0W4 203-578 None
A0A4Y7ICD5 21-380 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.