DPCstruct | MC580

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)72 ± 6 aa
Standard deviation of domain lengths5.60
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score87.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)62.82
Pfam Score100.00
Assigned Pfam label(s) CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9Y385 1-61 MFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQA
A0A819JBX5 2-74 FPYIDNIHGKWHFNEIRAIFSRRYLLQDKALEIFVSNRTSVMFAFIDRSIVKKVVNFLPRVGVGGRYGLPQQR
A0A212FNE6 81-161 None
M7BV09 25-97 None
A0A4Z2JCS3 1-61 None
A0A1X7SSK5 199-276 None
A0A3M7S4E8 7-79 None
A0A183MHP7 159-237 None
Q19317 1739-1811 None
A0A821R765 71-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.