DPCstruct | MC579

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)386 ± 30 aa
Standard deviation of domain lengths30.18
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)27.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1SC54 180-555 VSEISADGFVLLAANAQRDIYTLDFGDSGWTRRWGPLFWLDMGVTIPPDVTHWAASELHSGFDDYFVDIAGRKNDFWGILMLYMLRG…
A0A5P2D914 11-393 ITGISVDDDELAAVDDGGRIYTMDHALNAPWTWNWTHRYGTPLWLGDGNTVPYGSARWTWSVLSPGEDRVWRDTAGNDHPVGGAKVS…
A0A817MIV2 1-347 None
A0A496XNN6 131-564 None
A0A815LR14 12-366 None
E1R744 143-555 None
A0A2N2JPR7 107-525 None
A0A2W5T201 25-386 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.