DPCstruct | MC5780

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)123 ± 14 aa
Standard deviation of domain lengths13.58
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.83
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A818TMT5 7-136 TTAPRWRRARRGLCLEGQCPTSACEAFNRTVIMSLGFRRFDMLSDVGLATTKCPICKQYVEPVTCSFNNCWWRYEGIKRSQSQAPES…
A0A078AI22 180-300 KDDAPWYREISDGLSWICYCQNPKCFAFSQMVVINKGYGVYSINKEMQSIRCPCCLNGKFLEVRNCGFVNCEWAMRGILNKNKESKI…
A0A813TW76 2-125 None
A0A5J4VUN0 22-144 None
A0A388LFB8 327-449 None
A0A433QFH2 183-305 None
A0A433Q349 53-183 None
A0A1V9Y651 689-821 None
G4ZCC0 44-162 None
A0A814VFZ4 15-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.