DPCstruct | MC5755

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)152 ± 29 aa
Standard deviation of domain lengths29.07
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.67
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)30.57
Pfam Score98.68
Assigned Pfam label(s) CL0323- CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4YQM8 188-273 RVSDQLCDEEKEFLARRKKVATAALARYLGLEEQDINPEDVPTIAVCGSGGGLRALVAGTGSLLAIQEDGLLDCVTYTSGVSGSCW
A0A1D2VJB9 103-274 RNISASNEDENDNQYNHYNPIKNYAPYTTLCPLNERLVRSAYFDGLNQPSSQLSLSLEEQNYIANRQQKTQVALENYLNRISIDGFN…
A0A178EP78 1-124 None
A0A4U0VD14 27-161 None
A0A5N6ERM0 7-159 None
A0A2K0W9C8 8-146 None
A0A420NJB4 8-159 None
A0A0F4YG37 2-147 None
X0GUP1 12-162 None
B8P601 34-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.