DPCstruct | MC57383

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)84 ± 8 aa
Standard deviation of domain lengths7.53
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.66
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)60.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445MHW6 1-84 MDDELLQAVKDLESARAELPRQSVAQYKESLSFKEGLKRMGRVAYEYGYRVALARFRTRHPNADVEEDPFTIHPEDDLVPMERQ
A0A427AEB8 1-74 METELLELARSKDALQEDLPRRAIEDYKKSLGFEMGLVRMGRVSLEYGYQLALARLQARHPGVEIELDPFVSLP
A0A427B5X3 1-79 None
A0A426ZFG9 1-81 None
A0A4S8IZE4 1-102 None
A0A426Z9I1 1-84 None
A0A444CF81 153-236 None
A0A426XL57 196-290 None
A0A444BW97 1-84 None
A0A426X6D6 1-68 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.