DPCstruct | MC57359

Metacluster Properties and Pfam Annotations

Number of structural domains364
Mean domain length (aa)145 ± 29 aa
Standard deviation of domain lengths29.15
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score84.82
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.28
Pfam Score81.14
Assigned Pfam label(s) CL0179- CL0021- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8QL91 8-141 SKYVPKRSTDWLKVKTIMRAEVVVGGYTQPRGRRSYFGSLVCGLYRDDGLRYVAHVGGGFNERKLASIYKLMQPLKTGKSSFVDVPK…
A0A6F8NUA8 2-99 TIAGFALDGTKWDGIYVGRRKGDDLVYAGKVDHGFDKVSAADLQRRLRPLIRKTQPYTKRIGHKGIWVEPKLLAEIEYRAKSAEGKV…
K2DB73 1-137 None
A0A2H6KHK0 845-1000 None
A0A497I9D4 240-373 None
A0A554UJ28 54-183 None
A0A0D2FPM1 2-145 None
A0A257MDK1 92-233 None
A0A2W1BSD6 116-279 None
A0A4Q0PH21 6-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.