DPCstruct | MC5726

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)150 ± 12 aa
Standard deviation of domain lengths11.94
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.25
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)36.20
Pfam Score100.00
Assigned Pfam label(s) PF05681

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X1LCF7 2-129 FFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPGRSKVL…
A0A640KMB1 238-382 LPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGVWNAYKYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGG…
A0A654HEF7 350-498 None
A0A2X3EZX5 2-123 None
A0A350M0A9 63-192 None
A0A4R9LS92 60-231 None
A0A800C9S1 4-164 None
A0A1J1H7C8 174-344 None
A0A2X3CR52 3-156 None
A0A388NRQ0 101-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.