DPCstruct | MC57246

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)385 ± 74 aa
Standard deviation of domain lengths74.06
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score71.07
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.09
Pfam Score82.15
Assigned Pfam label(s) PF02671- PF08295

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B6A3P5 77-495 VEGNGIVDADVEAVVVNPLLQKPIDFLSGLKACPNMSDDHYAAFLKIMQDYFRDRTMTPRKVYKKVRRCMRDCPELLEEFVDNFLPA…
A0A183DYV7 1-311 MRRIFSDYATSRKLGPSYRALPDSYEKPLCSGRTPLCDSVLNDRWVSFPSWSSEESSCVLPKKTEFEEFMFRTDDERYELDIIIEIN…
A0A0V1BK92 42-373 None
A0A0C2MR01 81-497 None
A0A6S8VHN3 19-523 None
A0A6S8VSI8 1-324 None
A0A6J3CBY4 7-324 None
M4CWY0 54-295 None
A0A1X0S7P1 172-618 None
R0KLC8 2-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.