DPCstruct | MC57225

Metacluster Properties and Pfam Annotations

Number of structural domains782
Mean domain length (aa)90 ± 16 aa
Standard deviation of domain lengths16.44
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.14
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.24
Pfam Score94.38
Assigned Pfam label(s) CL0161- CL0183- CL0257- CL0304- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R4LSU2 85-178 ALRRSRADLVGSCGRAGSSIGSAPCPDESAIFVRLTDRERRVLILIAEGLTNRGIARRLRISEKTVRNHVHAIFCKLGVRSRTEAAL…
A0A527FXL8 2-63 SQLTGREAEILGLVAEGLSNKEVAMRLSLQEKTVKHHMTRVLAKLNVRNRTEAALLMHEARE
A0A848CMU3 112-182 None
A0A7W0PBF3 103-198 None
A0A3T0K545 129-229 None
A0A554V829 805-871 None
A0A3E4QRA9 55-182 None
A0A2V2DWT7 513-606 None
A0A160F2Q2 418-500 None
A0A7K2XUH9 116-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.