DPCstruct | MC5709

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)350 ± 77 aa
Standard deviation of domain lengths76.90
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.26
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)34.35
Pfam Score85.71
Assigned Pfam label(s) PF00082- PF02877

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q7E444 1-266 MPLSSTGVAQFRGHHPTYDGRGVVIGILDSGIDPGAPGLAVTTTGAPKILDLRDFSDEGRVSLTPVTPSPQGTVRVAGRALAGAGRI…
Q4RH92 51-435 APGMQVTTEGKPKIIDIIDTTGSGDVNMTTIAEPKDGTITGLSGRTLKIPPAWVNPSGKYRIGVKNGYEFFPKALKERIQKERKEKM…
X1WIL3 14-383 None
A0A7R8W9N3 293-613 None
A0A1W9RI96 34-309 None
A0A6H5GJE3 20-388 None
A0A3L6VQH8 41-385 None
A0A3Q0KLT9 10-590 None
A0A438E2Q3 84-509 None
A0A819Z1B8 16-381 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.