DPCstruct | MC56998

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)206 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score91.67
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)23.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V4LQ04 21-178 LKGTPGYFRIARTCKGQWWFLDPENKPFYYKGVCAVNRAGTPGGRRADPGPYAATVNKKYHYQAGVDSFISACIGKIKELNFNALGA…
M5TDS3 182-361 LAANPGPRNRNRYGGWVTGPQLESTGRFRTQKRNGKWWFVDPEGRLFWSQGITGVRLSQSTQTRGRENYFTEIHEGGDFRIANLKRK…
A0A5C6D317 29-224 None
A0A6I3RJF4 70-320 None
R6X2K2 262-489 None
A0A1G2ZGL0 269-495 None
A0A842W3S6 45-260 None
A0A4Q3VB79 4-191 None
D2VAY6 246-441 None
A0A2E6TMH3 757-940 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.