DPCstruct | MC56989

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)211 ± 23 aa
Standard deviation of domain lengths22.70
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.28
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.86
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H5X254 9-194 MNPAWVSVLRYSCRWAFQAQDEPTAARKVTNALHLWGAYQEGIWFARNYDDISETFYLRQCLERLEADGTVGQCNDFADLLLCLQTS…
A0A7V2Z1F6 473-690 SGLTAACVKKTSDTWQWKAGNFNGLGTNEIDANISGQHNLFVVLGEPSSPWSNTYGSACNAWRTVLDRSCDWADSATNEAGAVEMIT…
A0A7J4PIK4 10-225 None
A0A847YAL6 7-233 None
A0A7C7VAY8 52-265 None
A0A3C0BGR0 114-348 None
A0A847K142 45-239 None
A0A1B9NA30 183-402 None
A0A847JXX3 168-359 None
A0A2M7S9G4 1-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.