DPCstruct | MC56968

Metacluster Properties and Pfam Annotations

Number of structural domains288
Mean domain length (aa)233 ± 56 aa
Standard deviation of domain lengths56.24
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score83.39
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.69
Pfam Score83.85
Assigned Pfam label(s) PF04406- PF09660- PF11795- PF20768- PF10172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L7JUK4 32-282 EIIHGMLVDNVKKTKREIFYASPNIFKRQETVNKMIDKFAHVHKVRLIDFNVSASLKGLFYGEVTFIESNKAYTLYQNLIPDMNEVT…
K1TG56 6-144 IKNVRKILFIENKANYIDYIQNKQESDEFVIYHGGMYSPIKGKFFKKIYEACENQEFYHWSDIDIGGFRIFTRLKKIIPELQEYKMD…
A0A0Q4XQA8 117-319 None
A0A7J0G9F4 1-195 None
A0A1Q9SLF6 6-163 None
A0A843X7B1 208-473 None
A0A0D3H3V7 246-507 None
A0A517ZGW6 227-547 None
A0A7W1HN18 12-292 None
A0A6A6A0M1 135-459 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.