DPCstruct | MC56860

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)621 ± 112 aa
Standard deviation of domain lengths112.48
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.50
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.25
Pfam Score87.31
Assigned Pfam label(s) CL0023- PF12777- CL0671- PF18199

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9MMH5 65-663 HVLERIQPLEREQAGLLENMRKTESRKNKLENQLNSVGAKVNELKEKFQCHTTEAAKLEAEVTKAQDTITAAQQLLSQLEGEHTRWN…
A0A822BEF2 2-562 RVDLQPLSIMIDDADIAEWMNQGLPADQTSYENAAILIYCLRWPLMVDPQGQGLRWIKNLFTDKLVTLRYNSKGYLDRVEAAVRRGD…
A0A2P8YMB4 415-1207 None
A0A2K1INX7 515-1006 None
W2P9Z5 165-849 None
A0A0D8XQC7 331-926 None
A0A822DYW5 121-767 None
E7FFM4 1469-2142 None
A0A2V2VUL2 2-584 None
A0A3Q0IRD1 255-863 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.