DPCstruct | MC56756

Metacluster Properties and Pfam Annotations

Number of structural domains76
Mean domain length (aa)301 ± 63 aa
Standard deviation of domain lengths63.34
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score80.11
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)31.92
Pfam Score76.93
Assigned Pfam label(s) PF04990- PF04992- PF04998- PF05000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1H0L1 44-226 MIACVGQQAINGKRVPNGFENRALPHFEKFSKIPASRGFVENSFFSGLTPTEFFFHTMAGREGLVDTAVKTAETGYLQRRLVKCLED…
A0A7I8J9I0 4-354 CVGQQNVEGKRIPFGFIGRTLPHFTKDDYGPESRGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTSETGYIQRRLVKAMEDIMV…
A0A821S139 307-701 None
A0A2H2IYM4 522-780 None
A0A6A4GUT0 148-496 None
A0A7C5X2T1 2-260 None
A0A815HE76 8-333 None
A0A2G3CZT3 346-602 None
A0A819MJ77 2-375 None
A0A086JWA6 20-333 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.