DPCstruct | MC5675

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)136 ± 10 aa
Standard deviation of domain lengths9.52
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score89.31
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)30.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2RTA9 6-123 GTPYGGEFGITVELGSVWGRRGIAPAVKTLLDGFISALHVHDLSSREHVAAALDEVGDGERLWELLNDPAMAILGPRRLVRPHGRGI…
A0A1F6H593 111-257 RGEIKPHSIWCAMKNGFVEVNNDHPSLYGIQIKVKAPIGTTINLASIVKPVLDGIISSFHTHNGSDIIELSERLAKLLGENEQTMEK…
A0A1Q8XX86 269-415 None
A0A3D5DWK8 74-200 None
A0A064CER7 91-225 None
A0A2W6CHR5 18-146 None
A0A7C5KT33 2-138 None
A0A329LH02 538-668 None
A6WG99 190-337 None
A0A2T0QIM0 126-272 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.