DPCstruct | MC56732

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)338 ± 50 aa
Standard deviation of domain lengths49.58
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score66.36
Mean fraction of residues predicted as intrinsically disordered0.61
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)29.25
Pfam Score100.00
Assigned Pfam label(s) PF15456

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W9J8Y2 1-318 MEPNAAYLNLRNGSYTPPTITTEVGNASRGHRRGDLESSGTMGRGLPREGSGLGTNNDPFVQRPESRRGKSLEQKAFEPLPIGLKQA…
A0A1S8BBH9 2-284 GYSNSNEPPTNTTPITGIPECASPERTVRGRDTSRGHHRKRSEQSIMDRGRPIARTTRERKASASASASAPSSSEKEGADTWKLPKG…
A0A425BTB1 267-577 None
A0A194X793 42-379 None
A0A4Q9NZ08 145-607 None
A0A6A6YIZ1 73-391 None
A0A2S6C732 1-292 None
A0A0B7KG16 4-319 None
A0A1B8C5N8 1-320 None
A0A1U7LTN6 321-707 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.