DPCstruct | MC56583

Metacluster Properties and Pfam Annotations

Number of structural domains164
Mean domain length (aa)167 ± 31 aa
Standard deviation of domain lengths31.32
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score73.31
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.54
Pfam Score87.55
Assigned Pfam label(s) PF07500- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D0VD43 9-145 SSEGGSVDNVRDKCVVMIYDALALDSTAERAIGIERAANKSMNFSTGNDYRAKMRSLFLNLKDKGNPALRNEIVLGYISTEKVASMS…
A0A423U1B4 66-185 APPTTDALRLKCREMLTNALKCSELPDGIVDTPESLGEQIEEAIYQEYRNTDAAYKNRLRSRVYNLKDSKNPQLRENVLRGVISPKR…
A0A5D2K0Y4 319-448 None
A0A212CDK9 80-265 None
L1LAH2 6-194 None
B6ACI6 4-160 None
A0A835RHA2 2-141 None
C1DYW1 12-178 None
A0A383W6S4 529-725 None
A0A372QNJ9 19-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.