DPCstruct | MC56456

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)116 ± 6 aa
Standard deviation of domain lengths5.79
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score86.07
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)69.29
Pfam Score100.00
Assigned Pfam label(s) PF04121

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4D300 392-506 GELVRFQAGVTMEILRLDAWYSSKDGSPEGPATYIVRGLCRRCCIPEVILRCMQVSVSLVESGNPLESHDELIELVASPETGFLHLF…
A0A5D2JH95 232-346 GELARFQAGVTLEISRLDAWFSSKDGSLDGPATYIVQGLCRRCCIPEVILRCMQVSVSLMESGNPFESHDQLIELVSSSETGFINLF…
A0A452XR19 168-283 None
A0A2G9HUX7 71-188 None
A0A452XR03 1-104 None
A0A0R0FJK7 134-251 None
B4FPH4 71-196 None
A0A2P2K3Y0 120-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.